How to stir up interest and " sheep " ?What to do?

All met people who give no indication of interest or no interest in what you say, if you have something to tell. They are inert, no interest and nothing else do not seek, they do not care for anything not happy, only gossip and complain. And you tell them something, and in response to silence. As these people stir, if you still have to act, something to explain to them, ask for advice ?